Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Model Systems/Therapeutic Targets$24,115,793.04
Fiscal Year: 2010
  

Download 2010 Model Systems/Therapeutic Targets projects (EXCEL)
Animal models mimicking behaviors of ASD and those that are being used to develop or test new drug treatments, as well as cell lines used to discover new drug targets or to screen potential drug candidates, are included in this subcategory.
Graph: The subcategories for Question 4 illustrate the many approaches to treatments and interventions supported by autism research funders. The largest amount of funding supported projects to develop Model systems and therapeutic targets (35%), followed by research on Behavioral interventions (29%). Medical/Pharmacologic interventions received 16% of funding, classroom-based interventions (Educational) received 10% of funding, and Technology-based interventions and supports received 7% of funding. The subcategories with the smallest amounts of funding included Occupational, physical, and sensory-based (2%) and Complementary, dietary, and alternative (1%).
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
Modeling and pharmacologic treatment of autism spectrum disorders in Drosophila McDonald, Thomas Q4.S.B Albert Einstein College of Medicine of Yeshiva University
Identifying genetic modifiers of rett syndrome in the mouse Buchovecky, Christine Q4.S.B Baylor College of Medicine
Neurobiological mechanism of 15q11-13 duplication autism spectrum disorder Anderson, Matthew Q4.S.B Beth Israel Deaconess Medical Center
Characterization of autism susceptibility genes on chromosome 15q11-13 Smith, Stephen Q4.S.B Beth Israel Deaconess Medical Center
Interaction between MEF2 and MECP2 in the pathogenesis of autism spectrum disorders - 1 Lipton, Stuart Q4.S.B Burnham Institute
Interaction between MEF2 and MECP2 in the pathogenesis of autism spectrum disorders -2 Nakanishi, Nobuki Q4.S.B Burnham Institute
Novel probiotic therapies for autism Patterson, Paul Q4.S.B California Institute of Technology
Analysis of cortical circuits related to ASD gene candidates Zador, Anthony Q4.S.B Cold Spring Harbor Laboratory
16p11.2: defining the gene(s) responsible Mills, Alea Q4.S.B Cold Spring Harbor Laboratory
Novel models to define the genetic basis of autism Mills, Alea Q4.S.B Cold Spring Harbor Laboratory
Systematic analysis of neural circuitry in mouse models of autism Osten, Pavel Q4.S.B Cold Spring Harbor Laboratory
Investigating the effects of chromosome 22q11.2 deletions Karayiorgou, Maria Q4.S.B Columbia University
Genomic imbalances at the 22q11 locus and predisposition to autism Gogos, Joseph Q4.S.B Columbia University
Role of UBE3A in neocortical plasticity and function Ehlers, Michael Q4.S.B Duke University
Functional study of synaptic scaffold protein SHANK3 and autism mouse model Jiang, Yong-Hui Q4.S.B Duke University
Neurogenetic model of social behavior heterogeneity in autism spectrum disorders Platt, Michael Q4.S.B Duke University
Characterization of the transcriptome in an emerging model for social behavior Thomas, James Q4.S.B Emory University
Genomic resources for identifying genes regulating social behavior Young, Larry Q4.S.B Emory University
Vasopressin receptors and social attachment Young, Larry Q4.S.B Emory University
Neural mechanisms of social cognition and bonding Young, Larry Q4.S.B Emory University
Neural mechanisms of social cognition and bonding Young, Larry Q4.S.B Emory University
Central vasopressin receptors and affiliation Young, Larry Q4.S.B Emory University
Central vasopressin receptors and affiliation Young, Larry Q4.S.B Emory University
The role of SHANK3 in the etiology of autism spectrum disorder Bangash, M. Ali Q4.S.B Johns Hopkins University
Dynamic regulation of Shank3 and ASD Worley, Paul Q4.S.B Johns Hopkins University