Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Early Signs and Biomarkers$21,333,738.17
Fiscal Year: 2010
  

Download 2010 Early Signs and Biomarkers projects (EXCEL)
Projects which use a variety of methods to search for signs of autism in very young children (generally under age 3) that could be used for diagnosis, such as eye-tracking, physiological measures, and autism-specific behavioral patterns are included in this subcategory. More examples include projects investigating metabolic measures, such as the levels of specific chemicals, hormones, or proteins in the blood that could be used as biomarkers of the disorder.
Graph: The four subcategories for research related to Question 1 (Diagnosis) illustrated a heavy focus on identifying Early signs and biomarkers for ASD. Characterizing Symptomology and developing Diagnostic and screening tools also received significant funding (24% and 20%, respectively). The smallest subcategory focused on identifying Intermediate phenotypes and subgroups of people with ASD (9%).
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
Defining high and low risk expression of emotion in infants at risk for autism Hannigen, Sarah Q1.L.A University of Pittsburgh
Misregulation of BDNF in autism spectrum disorders Hempstead, Barbara Q1.L.A Weill Cornell Medical College
Early identification of autism: A prospective study Iverson, Jana Q1.L.A University of Pittsburgh
Metabolic biomarkers of autism: Predictive potential and genetic susceptibility James, Sandra Q1.L.A Arkansas Children's Hospital Research Institute
Identification of lipid biomarkers for autism Kang, Jing Q1.L.A Massachusetts General Hospital
The ontogeny of social visual engagement in infants at risk for autism Klin, Ami Q1.L.A Yale University
Physical and clinical infrastructure for research on infants-at-risk for autism at Yale Klin, Ami Q1.L.A Yale University
Model diagnostic lab for infants at risk for autism Klin, Ami Q1.L.A Yale University
Brain-behavior growth charts of altered social engagement in ASD infants Klin, Ami Q1.L.A Yale University
ACE Center: Linguistic and social responses to speech in infants at risk for autism Kuhl, Patricia Q1.L.A University of Washington
RNA expression studies in autism spectrum disorders Kunkel, Louis Q1.L.A Children's Hospital Boston
Signatures of gene expression in autism spectrum disorders Kunkel, Louis Q1.L.A Children's Hospital Boston
Electrophysiological, metabolic and behavioral markers of infants at risk Nelson, Charles Q1.L.A Children's Hospital Boston
Infants at risk of autism: A longitudinal study Ozonoff, Sally Q1.L.A University of California, Davis
Oxytocin biology and the social deficits of autism spectrum disorders Parker, Karen Q1.L.A Stanford University
Temporal coordination of social communicative behaviors in infant siblings of children with autism Parlade, Meaghan Q1.L.A University of Pittsburgh
ACE Center: Clinical Phenotype: Recruitment and Assessment Core Pierce, Karen Q1.L.A University of California, San Diego
Studying the biology and behavior of autism at 1-year: The Well-Baby Check-Up approach Pierce, Karen Q1.L.A University of California, San Diego
ACE Network: A longitudinal MRI study of infants at risk for autism Piven, Joseph Q1.L.A University of North Carolina at Chapel Hill
Supplement to NIH ACE Network grant: "A longitudinal MRI study of infants at risk for autism" Piven, Joseph Q1.L.A University of North Carolina at Chapel Hill
A prospective multi-system evaluation of infants at risk for autism Bauman, Margaret Q1.L.B Massachusetts General Hospital
Analyses of brain structure and connectivity in young children with autism Nordahl, Christine Q1.L.B University of California, Davis
Amygdala structure & biochemistry in adolescents with autism Nacewicz, Brendon Q1.L.B University of Wisconsin - Madison
Cellular structure of the amygdala in autism Morgan, John Q1.L.B University of California, Davis
Emotion, communication, & EEG: Development & risk Messinger, Daniel Q1.L.B University of Miami