Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Genetic Risk Factors$50,791,860.61
Fiscal Year: 2010
  

Download 2010 Genetic Risk Factors projects (EXCEL)
Projects in this subcategory seek to identify new genes that are implicated in increased risk for ASD or to better understand genetic risk factors that were previously identified.
Graph: Genetic risk factors accounted for a majority of research funding in Question 3 in 2010 (63%). Gene-Environment studies received 25% of funding, Epigenetic studies 7%, and Environment studies 5%.
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
Illumina, Inc. No PI listed Q3.L.B Illumina, Inc.
The role of retrotransposons in autism spectrum disorders Kazazian, Haig Q3.L.B Johns Hopkins University
Understanding glutamate signaling defects in autism spectrum disorders Wang, Tao Q3.L.B Johns Hopkins University
Integrative genetic analysis of autistic brains Arking, Dan Q3.L.B Johns Hopkins University School of Medicine
The role of contactin-associated protein-like 2 (CNTNAP2) and other novel genes in autism Chakravarti, Aravinda Q3.L.B Johns Hopkins University School of Medicine
Comprehensive follow-up of novel autism genetic discoveries Daly, Mark Q3.L.B Massachusetts General Hospital
Investigation of genes involved in synaptic plasticity in Iranian families with ASD Santangelo, Susan Q3.L.B Massachusetts General Hospital
A recurrent genetic cause of autism Gusella, James Q3.L.B Massachusetts General Hospital
Genes disrupted by balanced genomic rearrangements in autism spectrum disorders Gusella, James Q3.L.B Massachusetts General Hospital
Role of TSC/mTOR signaling pathway in autism and autism spectrum disorders Ramesh, Vijaya Q3.L.B Massachusetts General Hospital
The role of the neurexin 1 gene in susceptibility to autism Gusella, James Q3.L.B Massachusetts General Hospital/Harvard Medical School
The transcription factor PLZF: A possible genetic link between immune dysfunction and autism Sant'Angelo, Derek Q3.L.B Memorial Sloan-Kettering Cancer Center
3/5-Elucidating the genetic architecture of autism by deep genomic sequencing Buxbaum, Joseph Q3.S.A Mount Sinai School of Medicine
Hypocholesterolemic autism spectrum disorder Porter, Forbes Q3.L.B National Institutes of Health
Genetic epidemiology of complex traits Bailey-Wilson, Joan Q3.L.B National Institutes of Health
The frequency of polymorphisms in maternal- and paternal-effect genes in autism spectrum Levine, Arnold Q3.L.B Princeton University
The impact of autism specific genomic variations on microRNA gene expression profile Scherer, Stephen Q3.L.B The Hospital for Sick Children
Simons Simplex Collection Site Fombonne, Eric Q3.L.B The Research Institute of the McGill University Health Centre
Identification and functional characterization of gene variants Persico, Antonio Q3.L.B Universita Campus Bio-Medico di Roma
Simons Simplex Collection Site Geschwind, Daniel Q3.L.B University of California, Los Angeles
ACE Network: A comprehensive approach to identification of autism susceptibility genes Geschwind, Daniel Q3.L.B University of California, Los Angeles
FOXP2-regulated signaling pathways critical for higher cognitive functions Konopka, Genevieve Q3.Other University of California, Los Angeles
ACE Center: Targeting genetic pathways for brain overgrowth in autism spectrum disorders Wynshaw-Boris, Anthony Q3.L.B University of California, San Diego
Whole-exome sequencing to identify causative genes for autism Gleeson, Joseph Q3.L.B University of California, San Diego
ACE Center: Imaging autism biomarkers + risk genes Glatt, Stephen Q3.Other University of California, San Diego