Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Model Systems/Therapeutic Targets$24,115,793.04
Fiscal Year: 2010
  

Download 2010 Model Systems/Therapeutic Targets projects (EXCEL)
Animal models mimicking behaviors of ASD and those that are being used to develop or test new drug treatments, as well as cell lines used to discover new drug targets or to screen potential drug candidates, are included in this subcategory.
Graph: The subcategories for Question 4 illustrate the many approaches to treatments and interventions supported by autism research funders. The largest amount of funding supported projects to develop Model systems and therapeutic targets (35%), followed by research on Behavioral interventions (29%). Medical/Pharmacologic interventions received 16% of funding, classroom-based interventions (Educational) received 10% of funding, and Technology-based interventions and supports received 7% of funding. The subcategories with the smallest amounts of funding included Occupational, physical, and sensory-based (2%) and Complementary, dietary, and alternative (1%).
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
Murine genetic models of autism Veenstra-Vanderweele, Jeremy Q4.S.B Vanderbilt University
Neural and cognitive mechanisms of autism Sur, Mriganka Q4.S.B Massachusetts Institute of Technology
Neural mechanisms of social cognition and bonding Young, Larry Q4.S.B Emory University
Neural mechanisms of social cognition and bonding Young, Larry Q4.S.B Emory University
Neurobiological mechanism of 15q11-13 duplication autism spectrum disorder Anderson, Matthew Q4.S.B Beth Israel Deaconess Medical Center
Neurobiology of mouse models for human chr 16p11.2 microdeletion and fragile X Bear, Mark Q4.S.B Massachusetts Institute of Technology
Neurobiology of sociability in a mouse model system relevant to autism Brodkin, Edward Q4.S.B University of Pennsylvania
Neurogenetic model of social behavior heterogeneity in autism spectrum disorders Platt, Michael Q4.S.B Duke University
Neurogenomics in a model for procedural learning Hilliard, Austin Q4.S.B University of California, Los Angeles
Neuroligin function in vivo: Implications for autism and mental retardation Powell, Craig Q4.S.B University of Texas Southwestern Medical Center
Neuropharmacology of motivation and reinforcement in mouse models of autistic spectrum disorders Malanga, C.J. Q4.S.B University of North Carolina School of Medicine
Novel, subtype selective potentiators of nicotinic acetycholine receptors Schulte, Marvin Q4.Other University of Alaska Fairbanks
Novel genetic animal models of autism Powell, Craig Q4.S.B University of Texas Southwestern Medical Center
Novel models to define the genetic basis of autism Mills, Alea Q4.S.B Cold Spring Harbor Laboratory
Novel probiotic therapies for autism Patterson, Paul Q4.S.B California Institute of Technology
Novel strategies to manipulate Ube3a expression for the treatment of autism and Angelman syndrome Roth, Bryan Q4.S.B University of North Carolina at Chapel Hill
NrCAM, a candidate susceptibility gene for visual processing deficits in autism Maness, Patricia Q4.S.B University of North Carolina at Chapel Hill
Optimization of methods for production of both ICSI- and SCNT derived baboon embryonic stem cells Schatten, Gerald Q4.S.B Southwest Foundation For Biomedical Research
Patient iPS cells with copy number variations to model neuropsychiatric disorders Ellis, James Q4.S.B The Hospital for Sick Children
Preclinical testing of novel oxytocin receptor activators in models of autism phenotypes Pedersen, Cort Q4.S.B University of North Carolina at Chapel Hill
Preclinical testing of novel oxytocin receptor activators in models of autism phenotypes Jarstfer, Michael Q4.S.B University of North Carolina at Chapel Hill
Preclinical testing of novel oxytocin receptor activators in models of autism phenotypes Moy, Sheryl Q4.S.B University of North Carolina at Chapel Hill
Regulation of gene expression in the brain Young, Walter Q4.S.B National Institutes of Health
Role of a novel Wnt pathway in autism spectrum disorders Reichardt, Louis Q4.S.B University of California, San Francisco
Role of L-type calcium channels in hippocampal neuronal network activity Owen, Scott Q4.S.B Stanford University