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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Biomarkers in Autism: Bridging Basic Research with Clinical Research

Principal Investigator

Principal Investigator

Bridgemohan, Carolyn

Description

Description

ASDs are currently diagnosed by behavioral observation. The purpose of this study is to identify and examine correlations between potential biochemical, behavioral and physical biomarkers in children with ASDs. The identification of clinically validated biomarkers for ASDs would form the basis for a paradigm shift in the way clinicians identify, diagnose and treat ASDs. Predictive biomarkers might allow for earlier identification of individuals at risk and targeting appropriate and earlier treatment. Correlation of biomarkers with physical and behavioral phenotypes could also help with predicting and tracking outcomes and potentially, in future, allow for targeting specific treatments. An additional purpose of the study is to investigate the feasibility of conducting autism biomarker research within the clinical setting in an effort to strengthen the Autism Consortium clinical network’s ability to conduct larger scale clinical translational research.

Funder

Funder

Simons Foundation

Fiscal Year Funding

Fiscal Year Funding

13947

Current Award Period

Current Award Period

2015-2015

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Project Link

Project Link

Biomarkers in Autism: Bridging Basic Research with Clinical Research (External web link)

Institution

Institution

Children's Hospital Boston

State/Country

State/Country

Massachusetts

Project Number

Project Number

412328

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
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