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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Novel Methods to Understand Brain Connectivity in Autism

Principal Investigator

Principal Investigator

Foss-Feig, Jennifer

Description

Description

One theory to explain the causes and symptoms of ASD is an imbalance between excitatory and inhibitory signals in the brain. Some brain cells may be too turned on, or not turned on enough. As a result, signals may not be relayed across the brain properly, including in areas associated with ASD, resulting in autism symptoms. This may explain some of the behavioral features of ASD, but this theory has not been demonstrated with data. Dr. Foss-Feig will engage participants on a number of behavioral tasks, and at the same time, non-invasively measure brain activity in real time to look at how different regions are connected. The new funding will be used to build on a study of this mechanism in schizophrenia and apply the methods to study autism. This will also allow the researchers to better understand the differences and similarities between autism and schizophrenia, so new treatment strategies, including pharmacologic therapies, can be00 tested.

Funder

Funder

Autism Science Foundation

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2014-2015

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.

Project Link

Project Link

Novel Methods to Understand Brain Connectivity in Autism (External web link)

Institution

Institution

Yale University

State/Country

State/Country

Connecticut

Project Number

Project Number

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Novel Methods to Understand Brain Connectivity in Autism | 5000 | 2014 |

 
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