When people interact, a great deal of important information is exchanged through the eyes and the face. Processing this information and recognizing its meaning is a remarkable capacity of the human social cognitive system. For many individuals with autism spectrum disorders (ASDs), however, everyday interactions come with difficulties that point to deficits in parsing social cues. Identifying when and how these deficits emerge is a critical question with profound implications for early diagnosis and clinical intervention of ASDs. This project explores both the developmental time course and neural basis of social difficulties in ASD. Specifically, we study the brain’s response to robust sources of social information, such as eye contact, facial expression, and emotional valence, to search for potential early indicators of atypical development.