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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Identifying early biomarkers for autism using EEG connectivity

Principal Investigator

Principal Investigator

Levin, April

Description

Description

Siblings of children with autism have a likelihood of developing autism that is nearly twenty times higher than that of the general population. Studying potential biologic predictors of autism early in life before a behavioral diagnosis can be made, and then determining which of these children ultimately merit a diagnosis of autism, can therefore provide important information about early predictors of autism.  EEG is an ideal test for potentially predicting autism for several reasons. First, prior studies suggest that connections between neurons in the brain are different in children with autism, and that these connections can be assessed using EEG.  Additionally, EEG is noninvasive, does not require sedation, and allows evaluation of brain activity without a child’s active behavioral participation.  This study will evaluate the use of EEG-based brain connectivity as a predictor of future autism diagnosis by determining if infants with certain early EEG features are more likely to go on to be diagnosed with autism at age 3. Ultimately, this study has potential to inform future development of a clinically useful, easily administered, cost effective early screening test for autism.

Funder

Funder

Autism Science Foundation

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2012-2013

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Project Link

Project Link

Identifying early biomarkers for autism using EEG connectivity (External web link)

Institution

Institution

Boston Children's Hospital

State/Country

State/Country

Massachusetts

Project Number

Project Number

n/a

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Identifying early biomarkers for autism using EEG connectivity | 40000 | 2012 | N/A

 
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