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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Imaging-based real-time feedback to enhance therapeutic intervention in ASD

Principal Investigator

Principal Investigator

Liu, Ning

Description

Description

Functional near infrared spectroscopy (fNIRS) is a new, state-of-the-art neuroimaging method. It is safe, portable, easy to use, patient-friendly and cost-effective. fNIRS allows measurement of brain function in a naturalistic environment (e.g., sitting and conversing) and can be used to provide real-time monitoring of dynamic brain activity. Autism spectrum disorder (ASD) is the most compelling among all brain-based disorders with respect to impact on the life of the affected individual, and the wide variation in symptoms and severity. Since there is currently no cure for autism, a focus on the development of new, more effective therapeutic interventions could significantly improve the quality of life for those with ASD. This project will develop a highly novel fNIRS-based paradigm to enhance the effectiveness of behavioral interventions focused on social cognition. Specifically, the investigators will utilize fNIRS to enable clinicians to quantitatively determine brain activation of their patients in real-time, and provide feedback to their patients based on neural circuitry as well as behavioral response. This project will accelerate the translation of fNIRS functional imaging to enhance the treatment of ASD. The initial stage of the research training will provide fundamental knowledge of ASD including diagnostic procedures, evidence-based clinical interventions and prevailing theories of contributory neurobiology. The fellowship experience will also provide training in fNIRS signal processing and analysis within a bioengineering context. The collective training has the potential to lead to translational biomedical imaging, and to develop more effective methods and devices to treat ASD. - See more at: http://science.grants.autismspeaks.org/search/grants/imaging-based-real-time-feedback-enhance-therapeutic-intervention-asd#sthash.GRs5qBjc.dpuf

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

59825

Current Award Period

Current Award Period

2013-2015

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2LB. Launch at least three studies which evaluate the applicability of ASD phenotype and/or biological signature findings for performing diagnosis, risk assessment, or clinical intervention by 2015. IACC Recommended Budget: $7,200,000 over 5 years.

Project Link

Project Link

Imaging-based real-time feedback to enhance therapeutic intervention in ASD (External web link)

Institution

Institution

Stanford University

State/Country

State/Country

California

Project Number

Project Number

8681

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Imaging-based real-time feedback to enhance therapeutic intervention in ASD | 61530 | 2014 | 8681
Imaging-based real-time feedback to enhance therapeutic intervention in ASD | 0 | 2015 | 8681

 
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