Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders

Principal Investigator

Principal Investigator

Yoshii, Akira

Description

Description

Akira Yoshii, M.D., Ph.D., Massachusetts Institute of Technology will study a genetic syndrome called Tuberous Sclerosis Complex (TSC) that sometimes accompanies ASD. Using two-photon microscopy and molecular imaging, he will seek to determine if serotonin synapses are dysregulated in TSC, providing information on the causal relationship between dysregulated serotonin function during early brain development and ASD.

Funder

Funder

Brain & Behavior Research Foundation

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2014-2016

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Project Link

Project Link

No link available.

Institution

Institution

Massachusetts Institute of Technology

State/Country

State/Country

Massachusetts

Project Number

Project Number

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders | 0 | 2014 |
Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders | 0 | 2015 |

 
Back to Top