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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

GABA and Gamma-band Activity: Biomarker for ASD?

Principal Investigator

Principal Investigator

Port, Russell

Description

Description

The differences in brain activity that generate the symptoms of ASD are not understood, yet it is this very activity that is targeted by treatment. This research aims to directly study brain activity by measuring the magnetic signals generated by the brain as it responds to sound. Our research suggests that a certain kind of activity in the brain (gamma-band) is disrupted in children with ASD, and differences in the inhibitory neurochemical GABA is involved. By targeting the underlying biology, this research may allow us to determine which treatments are effective earlier and on an individual basis, and guide treatment development.

Funder

Funder

Autism Science Foundation

Fiscal Year Funding

Fiscal Year Funding

25000

Current Award Period

Current Award Period

2013-2014

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Project Link

Project Link

GABA and Gamma-band Activity: Biomarker for ASD? (External web link)

Institution

Institution

University of Pennsylvania

State/Country

State/Country

Pennsylvania

Project Number

Project Number

n/a

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

GABA and Gamma-band Activity: Biomarker for ASD? | 0 | 2014 |

 
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