A striking number of genes associated with a spectrum of neuropsychiatric
disorders (NPD) were found to be disrupted in subjects with
ASD and related neurodevelopmental disorders (NDD). Employing innovations in sequencing and bioinformatics developed during his
postdoctoral research, Dr. Talkowski seeks to prove that careful
genomic approaches can elucidate locations at which some genetic
changes confer risk for NPD and NDD.