Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Perinatal exposure to airborne pollutants and associations with autism phenotype

Principal Investigator

Principal Investigator

Volk, Heather

Description

Description

This study seeks to expand and integrate previous research on air pollutants to understand the effect of these environmental contaminants on autism, building on data in the Autism Genetic Resource Exchange (AGRE). Current studies have been limited to specific regions, however, access to AGRE families provides the opportunity to study potential environmental contributors to autism over a broad geographic area, and further creates the potential for gene-environment research. In this study AGRE families will be re-contacted to collect information on residential histories of the parents during pregnancy and early life of each child in the family. Addresses will be geocoded, and air pollution assignments created for each location using Environmental Protection Agency (EPA) databases. These will include HAPs, air quality measurements (including PM), and distance to roadway metrics as an indicator of TRP. Addresses will also be linked to census data to gather important information on demographic and socioeconomic characteristics that may be important to air pollution-autism associations. This study will help in understanding how air pollutants, which are very common environmental exposures, may be part of the puzzle of what causes autism. By linking this environmental data to the existing AGRE data, this will create a resource that can be used for future studies that could include how a person's genetic makeup may increase susceptibility to air pollutants.

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

149737

Current Award Period

Current Award Period

2011-2014

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SC. Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene – environment research by 2011. IACC Recommended Budget: $27,800,000 over 5 years.

Project Link

Project Link

Perinatal exposure to airborne pollutants and associations with autism phenotype (External web link)

Institution

Institution

University of Southern California

State/Country

State/Country

California

Project Number

Project Number

7785

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Perinatal exposure to airborne pollutants and associations with autism phenotype | 0 | 2011 | 7785
Perinatal exposure to airborne pollutants and associations with autism phenotype | 102717 | 2012 | 7785
Perinatal exposure to airborne pollutants and associations with autism phenotype | 166100 | 2014 | 7785
Perinatal exposure to airborne pollutants and associations with autism phenotype | 0 | 2015 | 7785

 
Back to Top