Autism Research Database - Strategic Plan Objective Project Details | IACC

Project Element	Element Description
Project Title Project Title	In utero antidepressant exposures and risk for autism
Principal Investigator Principal Investigator	Perlis, Roy
Description Description
Funder Funder	National Institutes of Health
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	$343,560
Current Award Period Current Award Period	2013-2016
Strategic Plan Question Strategic Plan Question	Question 3: What Caused This To Happen And Can This Be Prevented?
Strategic Plan Objective Strategic Plan Objective	Support at least three studies of special populations or use existing databases to inform our understanding of environmental risk factors for ASD in pregnancy and the early postnatal period by 2012. Such studies could include: o Comparisons of populations differing in geography, gender, ethnic background, exposure history (e.g., prematurity, maternal infection, nutritional deficiencies, toxins), and migration patterns; and o Comparisons of phenotype (e.g., cytokine profiles), in children with and without a history of autistic regression, adverse events following immunization (such as fever and seizures), and mitochondrial impairment. These studies may also include comparisons of phenotype between children with regressive ASD and their siblings. Emphasis on environmental factors that influence prenatal and early postnatal development is particularly of high priority. Epidemiological studies should pay special attention to include racially and ethnically diverse populations.
Subcategory Subcategory	Environment
Funder’s Project Link Funder’s Project Link	NIH RePORTER Project Page
Institution Institution	Massachusetts General Hospital
Institute Location Institute Location	Massachusetts
Project Number Project Number	1R01MH100286-01
Federal or Private Federal or Private	Federal
History/Related Projects History/Related Projects	N/A

Back to Top