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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Elevated urinary P-cresol in small autistic children: Origin and consequences

Principal Investigator

Principal Investigator

Persico, Antonio

Description

Description

This study assesses gut permeability, urinary p-cresol, fecal c. difficile/toxin A/calprotectin and urinary cotinine. In addition, the study implements a fecal metabolomic approach to assess gut microbiota beyond c.difficile in order to exclude infection by other cresol-producing bacteria and to point convincingly toward environmental exposure as the cause of elevated urinary p-cresol in autism.

Funder

Funder

Autism Research Institute

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2012-2013

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 3SI. Support at least two studies that examine potential differences in the microbiome of individuals with ASD versus comparison groups by 2012. IACC Recommended Budget: $1,000,000 over 2 years.

Project Link

Project Link

Elevated urinary P-cresol in small autistic children: Origin and consequences (External web link)

Institution

Institution

Universita Campus Bio-Medico di Roma

State/Country

State/Country

Italy

Project Number

Project Number

2012-2

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Elevated urinary P-cresol in small autistic children: Origin and consequences | 20000 | 2012 | 2012-2

 
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