Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

The Effects of Oxytocin on Social Reciprocity in Individuals with ASD

Principal Investigator

Principal Investigator

Stavropoulos, Katherine

Description

Description

Improved understanding of the brain basis of social motivation in autism spectrum disorder (ASD) is needed to develop scientifically-informed treatments. Although joint attention is a key focus of interventions, the passive nature of most neuroscience research has offered little direct insight into activity in reward systems during interactions with a social partne0r. This project combines eye-tracking and electrophysiology to study joint attention in a simulated face-to-face interaction. This paradigm will allow us, for the first time, to identify biological markers of reward anticipation in the context of shared attention. To investigate the responsiveness of these markers to intervention, we have developed game-based paradigms designed to shape pro-social patterns of gaze. We will use these paradigms after administration of oxytocin versus placebo to test the hypothesis that administration of oxytocin facilitates social learning. This innovative research aims to shed light on the biological basis of self-motivated social behavior.

Funder

Funder

Autism Science Foundation

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2014-2015

Strategic Plan Question

Strategic Plan Question

Question 4: Which Treatments And Interventions Will Help?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 4LC. Conduct at least one study to evaluate the safety and effectiveness of medications commonly used in the treatment of co-occurring conditions or specific behavioral issues in people with ASD by 2015. IACC Recommended Budget: $10,000,000 over 5 years.

Project Link

Project Link

The Effects of Oxytocin on Social Reciprocity in Individuals with ASD (External web link)

Institution

Institution

Yale University

State/Country

State/Country

Connecticut

Project Number

Project Number

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

The Effects of Oxytocin on Social Reciprocity in Individuals with ASD | 35000 | 2014 |

 
Back to Top