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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Interdisciplinary investigation of biological signatures of autism subtypes

Principal Investigator

Principal Investigator

Amaral, David

Description

Description

A major roadblock to preventing and more adequately treating autism is that there are many causes and many types. It is currently impossible to determine what type of autism a child has at diagnosis. In order to solve this problem, this study will examine the biology of a large number of children with autism to identify biological signatures of different types of autism. As an extension of the Autism Phenome Project at the M.I.N.D. Institute, preschoolers with ASD and with typical development (TD) will receive full medical evaluation, medical record review, environmental exposure assessment, blood based genetic and immune profiling, structural magnetic resonance imaging (MRI), EEG based studies of auditory processing, and comprehensive developmental and neuropsychological evaluations. This research will lead to identification of several subtypes of autism, which will enable more effective efforts at preventing future cases of autism and treating children with an existing autism diagnosis.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

1429402

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 2LA. Complete a large-scale, multi-disciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020. IACC Recommended Budget: $126,200,000 over 12 years.

Project Link

Project Link

Interdisciplinary investigation of biological signatures of autism subtypes (External web link)

Institution

Institution

University of California, Davis

State/Country

State/Country

California

Project Number

Project Number

1R01MH089626-01

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

Yes

History/Related Projects

History/Related Projects

Interdisciplinary investigation of biological signatures of autism subtypes | 1398688 | 2010 | 5R01MH089626-02

 
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