Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Brain glutamate concentrations in autistic adolescents by MRS

Principal Investigator

Principal Investigator

Anagnostou, Athanasius

Description

Description

Previous studies have suggested that the glutamate system may be abnormal in the brain of adolescents with autism and that these abnormalities may arise after early childhood. A non-invasive way of measuring glutamate in the brain is by using magnetic resonance spectroscopy (MRS). This technique is based on the same principles as magnetic resonance imaging (MRI), but, instead of images, it provides high frequency spectra that allow the investigators to study the biochemical composition of the brain. In this research, the glutamate concentrations in the brains of adolescents (12-17 years) will be compared between children that are typically developing and those that have autism. The goal of the study is to determine whether adolescents with autism exhibit increased glutamate concentrations.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

1224

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SE. Support at least two studies to determine if there are subpopulations that are more susceptible to environmental exposures (e.g., immune challenges related to infections, vaccinations, or underlying autoimmune problems) by 2012. IACC Recommended Budget: $8,000,000 over 2 years.

Project Link

Project Link

Brain glutamate concentrations in autistic adolescents by MRS (External web link)

Institution

Institution

Mount Sinai School of Medicine

State/Country

State/Country

New York

Project Number

Project Number

5M01RR000071-46

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Brain glutamate concentrations in autistic adolescents by MRS | 9703 | 2008 | M01RR000071-45

 
Back to Top