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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Intransal oxytocin in the treatment of autism

Principal Investigator

Principal Investigator

Anagnostou, Athanasius

Description

Description

There is accumulating evidence that oxytocin, produced by the hypothalamus, plays a key role in social cognition and attachment, repetitive behaviors, and anxiety. Based on such data, abnormalities in the oxytocin system may be responsible for some of the core and associated deficits seen in autism. In this study, intranasal oxytocin will be assessed as a treatment for ASD in adults with high functioning autism or Asperger's syndrome. The effect of oxytocin vs. placebo will be assessed using measures of social cognition, repetitive behaviors, irritability, and anxiety. This study will also employ event related recordings to collect naturalistic data on some of the above symptom areas. An additional part of this study will examine the effects of oxytocin on gene expression.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

2202

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 4: Which Treatments And Interventions Will Help?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 4LA. Complete at least three randomized controlled trials on medications targeting core symptoms in people with ASD of all ages by 2014. IACC Recommended Budget: $22,200,000 over 5 years.

Project Link

Project Link

Intransal oxytocin in the treatment of autism (External web link)

Institution

Institution

Mount Sinai School of Medicine

State/Country

State/Country

New York

Project Number

Project Number

5M01RR000071-46

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Intransal oxytocin in the treatment of autism | 13127 | 2008 | M01RR000071-45

 
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