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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Prenatal factors and risk of autism in a Finnish national birth cohort

Principal Investigator

Principal Investigator

Brown, Alan

Description

Description

This research will investigate whether environmental factors during pregnancy are related to the likelihood that offspring will be diagnosed with autism. Environmental factors such as infections, immune abnormalities, hormones, and smoking will be assessed in pregnancies of 1,000 autism cases and 1,000 healthy children using maternal serum samples that were drawn and stored in nearly all pregnancies in Finland from 1987-2007. Children with autism and healthy children matched to the cases on sex, date of birth, birth place and residence in Finland will be identified from detailed national databases that contain diagnoses on nearly all cases of autism in Finland. Researchers will also test whether there are differences in susceptibility to these environmental factors between boys and girls with autism. This research has the potential to result in a better understanding of the different causes of autism and different developmental pathways that can lead to the illness. The discovery of these causes can lead to prevention of cases of autism by improved prenatal care and to the identification of children who are at risk of developing autism.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

840697

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 3SC. Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene – environment research by 2011. IACC Recommended Budget: $27,800,000 over 5 years.

Project Link

Project Link

Prenatal factors and risk of autism in a Finnish national birth cohort (External web link)

Institution

Institution

New York State Psychiatric Institute

State/Country

State/Country

New York

Project Number

Project Number

1R01ES019004-01

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

Yes

History/Related Projects

History/Related Projects

Prenatal factors and risk of autism in a Finnish national birth cohort | 408838 | 2010 | 5R01ES019004-02

 
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