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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Neural mechanisms underlying obsessive compulsiveness in ASD

Principal Investigator

Principal Investigator

Carrasco, Melisa

Description

Description

This is an individual National Research Service Award for pre-doctoral research training, which provides support for promising doctoral candidates who will be performing dissertation research and training in a scientific health-related field. From a public health perspective, it is imperative to learn more about the neural systems underlying obsessiveness and compulsiveness in autism spectrum disorders (ASD), given the high prevalence of these symptoms in ASD patients. Recent studies have identified functional abnormalities of the default network (i.e., a set of brain regions activated during passive task states and whose activity and function may play an important role in the development of several neuropsychiatric disorders). In addition, recent studies of ASD have shown that the disorder may be largely characterized by deficits in cognitive processes under the control of default mode structures (i.e., known to modulate social, emotional, self-relevant tasks) that might be due to dysfunction of the default network. The study proposed here aims to better understand this brain-behavior relationship. This knowledge may suggest new therapeutic routes and diagnostic techniques to help treat obsessive and compulsive symptoms in ASD.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

32236

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.

Project Link

Project Link

Neural mechanisms underlying obsessive compulsiveness in ASD (External web link)

Institution

Institution

University of Michigan

State/Country

State/Country

Michigan

Project Number

Project Number

1F31MH086273-01

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Neural mechanisms underlying obsessive compulsiveness in ASD | 32934 | 2010 | 5F31MH086273-02

 
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