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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

ACE Center: Structural and chemical brain imaging of autism

Principal Investigator

Principal Investigator

Dager, Stephen

Description

Description

This grant provides support for an NIH Autism Center of Excellence (ACE). This study seeks to identify early manifestations of abnormal brain development in autism spectrum disorders (ASD). Twelve-month old infant siblings of children with autism, and comparison non-risk infants, will be studied using magnetic resonance imaging (MRI) and magnetic resonance spectroscopic imaging (MRSI), and relationships between brain measures and clinical course and symptom onset will be examined. A second part of the research will examine children entering adolescence in order to identify brain developmental changes that may be related to onset seizure and behavioral decline during the adolescent period. This study will enable understanding of the relationship between variations in brain development and longer-term clinical outcome, focusing on adolescent seizure onset and cognitive decline.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

521038

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2SE. Launch three studies that target the underlying biological mechanisms of co-occurring conditions with autism including seizures/epilepsy, sleep disorders and familial autoimmune disorders by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Project Link

Project Link

ACE Center: Structural and chemical brain imaging of autism (External web link)

Institution

Institution

University of Washington

State/Country

State/Country

Washington

Project Number

Project Number

5P50HD055782-03

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

ACE Center: Structural and chemical brain imaging of autism | 514982 | 2010 | 5P50HD055782-04

 
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