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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Integrated function/structure image analysis in autism

Principal Investigator

Principal Investigator

Duncan, James

Description

Description

Functional magnetic resonance imaging (fMRI) studies in subjects with autism spectrum disorder (ASD) indicate that there may be differences in regional brain function in response to several different face recognition and social attribute discrimination tasks. In a few specific brain regions, fMRI has shown differences between normal controls and ASD subjects. However, these previous studies have been limited in terms of their ability to localize information spatially and to delineate subgroups within ASD. This proposed research is centered on developing unique mathematical approaches that consider functional and structural information together in order to develop more sensitive and spatially-specific measurements. These approaches will be tested in their ability to separate subgroups in the autism spectrum (autism, Asperger's, PDD-NOS) using both functional and structural measures.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

339441

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.

Project Link

Project Link

Integrated function/structure image analysis in autism (External web link)

Institution

Institution

Yale University

State/Country

State/Country

Connecticut

Project Number

Project Number

5R01NS035193-12

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Integrated function/structure image analysis in autism | 339800 | 2008 | R01NS035193-11

 
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