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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Genome-wide association study of autism characterized by developmental regression

Principal Investigator

Principal Investigator

Molloy, Cynthia

Description

Description

By some estimates, up to 30% of children with autism experienced developmental regression characterized by the acquisition and subsequent loss of social and communication skills. Dr. Molloy plans to explore the genetic component of this devastating phenomenon by analyzing and comparing the genetic "profile" of children with autism affected by regression with normally developing counterparts. By focusing on a more homogenous subset of the population, she and her colleagues hope to identify autism susceptibility genes, especially those that might be related to regression.

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

127458

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SE. Support at least two studies to determine if there are subpopulations that are more susceptible to environmental exposures (e.g., immune challenges related to infections, vaccinations, or underlying autoimmune problems) by 2012. IACC Recommended Budget: $8,000,000 over 2 years.

Project Link

Project Link

Genome-wide association study of autism characterized by developmental regression (External web link)

Institution

Institution

Cincinnati Children's Hospital Medical Center

State/Country

State/Country

Ohio

Project Number

Project Number

1984

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Genome-wide association study of autism characterized by developmental regression | 127458 | 2010 | 1984
Genome-wide association study of autism characterized by developmental regression | 150000 | 2008 | 1984

 
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