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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Melatonin for sleep in children with autism: Safety, tolerability, and dosing

Principal Investigator

Principal Investigator

Malow, Beth

Description

Description

Children with neuropsychiatric conditions, such as autism spectrum disorders (ASD), are at high risk for insomnia, and pharmacological treatments for insomnia in this population are acutely needed. Lack of restorative sleep may exacerbate disabling behaviors associated with ASD. Treatments that promote sleep in children with ASD may ameliorate these behaviors as well as strengthen the ability of parents to cope with this disorder and to assist their children in overcoming their disabilities. The long-term objectives are to determine if supplemental melatonin is an effective treatment for insomnia in children with ASD and whether the use of melatonin to treat insomnia improves these children's daytime behaviors and reduces levels of parental stress.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

345401

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 4: Which Treatments And Interventions Will Help?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 4SA. Support at least three randomized controlled trials that address co-occurring medical conditions associated with ASD by 2010. IACC Recommended Budget: $13,400,000 over 3 years.

Project Link

Project Link

Melatonin for sleep in children with autism: Safety, tolerability, and dosing (External web link)

Institution

Institution

Vanderbilt University

State/Country

State/Country

Tennessee

Project Number

Project Number

5R01HD059253-02

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Melatonin for sleep in children with autism: Safety, tolerability, and dosing | 387141 | 2008 | R01HD059253-01A2
Melatonin for sleep in children with autism: Safety, tolerability, and dosing (supplement) | 140616 | 2009 | 3R01HD059253-02S1

 
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