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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Cerebral asymmetry and language in autism

Principal Investigator

Principal Investigator

Rojas, Donald

Description

Description

Preliminary evidence suggests that there is a reduction in the volume of the brain region planum temporale in both adults and children with autism. The planum temporale (PT) is an auditory processing brain region intimately associated with language processing in the left hemisphere in normal development. Using magnetic resonance imaging (MRI), the researchers will measure the volume of the left hemisphere PT in 20 parents of children with autism, 20 age-matched adults with autism, and 20 adults with no personal or familial history of autism. Language function and family history of language development will also be assessed in the same three groups of adults and correlated to the MRI findings. The researchers hypothesize that reduction in PT volume will be present in the parents of children with autism. Such a finding would bolster the hypothesis that PT volume reduction represents a familial risk factor for language delay in autism.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

6798

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2LB. Launch at least three studies which evaluate the applicability of ASD phenotype and/or biological signature findings for performing diagnosis, risk assessment, or clinical intervention by 2015. IACC Recommended Budget: $7,200,000 over 5 years.

Project Link

Project Link

Cerebral asymmetry and language in autism (External web link)

Institution

Institution

University of California, Los Angeles

State/Country

State/Country

California

Project Number

Project Number

5P41RR013642-12

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Cerebral asymmetry and language in autism | 2576 | 2008 | P41RR013642-11

 
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