Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Reward systems in children with autism

Principal Investigator

Principal Investigator

Scott, Ashley

Description

Description

This is an individual National Research Service Award for pre-doctoral research training, which provides support for promising doctoral candidates who will be performing dissertation research and training in a scientific health-related field. The basal ganglia (BG) system has been implicated in learning and memory, language, motor behaviors, and social communication, all of which are disrupted in autism spectrum disorders (ASD). This study will investigate the BG in autism as a possible core neurobiological component of the disorder using both structural and functional magnetic resonance imaging (fMRI). The study will use an established implicit learning task, which has been shown to rely on the BG, and add a reward component to test the hypothesis that ASD children will show less activity in this area compared to typically developing children. Beyond investigating functional deficits in the basal ganglia, this research will also explore the underlying link between neural structure to behavior by relating the functional and structural measures to measures of repetitive behaviors, restricted interests, and overall severity of autistic symptoms. By addressing relationships between behavior, structure, and function of one system in both children with and without autism, a clearer picture of how implicit learning and reward system dysfunction may contribute to some of the core deficits in autism will emerge.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

29840

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.

Project Link

Project Link

Reward systems in children with autism (External web link)

Institution

Institution

University of California, Los Angeles

State/Country

State/Country

California

Project Number

Project Number

5F31MH079645-02

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
Back to Top