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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Improving and streamlining screening and diagnosis of ASD at 18-24 months of age

Principal Investigator

Principal Investigator

Wetherby, Amy

Description

Description

The American Academy of Pediatrics recommends that all children be screened with an autism spectrum disorder (ASD)-specific screening tool at 18- and 24- months. However, there currently is not a well-validated ASD-specific screener for use at 18-24 months in pediatric settings, making the need for validated screening tools at these young ages urgent. This research project is designed to study the following screening and evaluation measures: 1) the Early Screening for Autism and Communication Disorders (ESAC), a new autism-specific parent report screening tool for children 12-36 months; 2) the Systematic Observation of Red Flags of ASD for a clinical setting (SORF-Clinic), 3) the Systematic Observation of Red Flags of ASD for a home setting (SORF-Home), and the Autism Diagnostic Observation Schedule (ADOS) Toddler Module newly developed for children under 30 months of age. A total of 600 children from 18-24 months of age will participate in this study. A best estimate clinical diagnosis will be made as the gold standard to compare the other tools. The expected outcomes of this study will have significance for the field by documenting the accuracy of a set of promising screening and evaluation measures for toddlers that maximizes the role of families to improve early detection of ASD. The comparison of autism symptoms displayed at home in everyday activities with those displayed in clinical settings will have important implications for building consensus with families of toddlers about early red flags of ASD and the urgency of early diagnosis and for developing more effective screening methods. These findings will advance science by providing researchers methods for identifying and hence studying children with ASD at younger ages, which could impact genetic, biomedical, and intervention research. By improving and streamlining early screening and diagnosis of ASD in 18 to 24 month old children, the findings of this study will have important implications for earlier access to intervention.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

971606

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1SB. Validate and improve the sensitivity and specificity of new or existing screening and diagnostic tools, including comparison of general developmental screening versus autism-specific screening tools, in both high risk and population-based samples through studies of the following community populations that are diverse in terms of age, socio-economic status, race, ethnicity, characteristics of ASD, and general level of functioning by 2012. IACC Recommended Budget: $5,400,000 over 3 years.

Project Link

Project Link

Improving and streamlining screening and diagnosis of ASD at 18-24 months of age (External web link)

Institution

Institution

Florida State University

State/Country

State/Country

Florida

Project Number

Project Number

1R01HD065272-01

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

Yes

History/Related Projects

History/Related Projects

Improving and streamlining screening and diagnosis of ASD at 18-24 months of age | 968011 | 2010 | 5R01HD065272-02

 
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