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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Toxicant-induced autism and mitochondrial modulation of nuclear gene expression

Principal Investigator

Principal Investigator

Wlodarczyk, Bogdan

Description

Description

This is a study of toxin exposure in utero and its effect on mitochondrial DNA level, DNMT1 (DNA (cytosine-5-)-methyltransferase 1) gene expression, and epigenetic changes of key developmental genes.

Funder

Funder

Department of Defense

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SF. Initiate studies on at least 10 environmental factors identified in the recommendations from the 2007 IOM report "Autism and the Environment: Challenges and Opportunities for Research" as potential causes of ASD by 2012. Estimated cost $56,000,000 over 2 years.

Project Link

Project Link

Toxicant-induced autism and mitochondrial modulation of nuclear gene expression (External web link)

Institution

Institution

Texas A&M University

State/Country

State/Country

Texas

Project Number

Project Number

AR080091

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Toxicant-induced autism and mitochondrial modulation of nuclear gene expression | 0 | 2010 | AR080091

 
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