Autism Research Database - Strategic Plan Objective Project Details

Project Element	Element Description
Project Title Project Title	Toxicant-induced autism and mitochondrial modulation of nuclear gene expression
Principal Investigator Principal Investigator	Wlodarczyk, Bogdan
Description Description	This is a study of toxin exposure in utero and its effect on mitochondrial DNA level, DNMT1 (DNA (cytosine-5-)-methyltransferase 1) gene expression, and epigenetic changes of key developmental genes.
Funder Funder	Department of Defense
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	$0
Current Award Period Current Award Period	na
Strategic Plan Question Strategic Plan Question	Question 3: What Caused This To Happen And Can This Be Prevented?
Strategic Plan Objective Strategic Plan Objective	Initiate studies on at least 10 environmental factors identified in the recommendations from the 2007 IOM report "Autism and the Environment: Challenges and Opportunities for Research" as potential causes of ASD by 2012. Estimated cost $56,000,000 over 2 years.
Funder’s Project Link Funder’s Project Link	External Project Page
Institution Institution	Texas A&M University
Institute Location Institute Location	Texas
Project Number Project Number	AR080091
Federal or Private Federal or Private	Federal
Received ARRA Funding? Received ARRA Funding?	No
History/Related Projects History/Related Projects	Toxicant-induced autism and mitochondrial modulation of nuclear gene expression \| $0.00 \| 2010 \| AR080091