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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Development of neural pathways in infants at risk for autism spectrum disorders

Principal Investigator

Principal Investigator

Dobkins, Karen

Description

Description

Because autism spectrum disorders (ASD) is not diagnosed reliably before the second or third year of life, the best way to investigate development of the disorder involves studying infant siblings of children with ASD (High-Risk infants), who have a significantly increased risk (10- to 20-fold) of developing ASD. This study uses a neurodevelopmental approach and a variety of techniques to identify abnormalities associated with High-Risk ASD infants (ages 6 to 36 months) by tracking their development in comparison to normal infants. Abnormalities in visual processing, motion processing, face processing, and social/emotional processing will be assessed. Standardized tests will also be used to evaluate social, communicative, and cognitive skills. The hope is that these studies will shed light on the neurodevelopmental origins of ASD (and the broader autism phenotype) and aid in early diagnosis of the disorder.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

325029

Current Award Period

Current Award Period

2008-2012

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Project Link

Project Link

Development of neural pathways in infants at risk for autism spectrum disorders (External web link)

Institution

Institution

University of California, San Diego

State/Country

State/Country

California

Project Number

Project Number

5R01HD052804-03

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Development of neural pathways in infants at risk for autism spectrum disorders | 328313 | 2009 | 5R01HD052804-02
Development of neural pathways in infants at risk for autism spectrum disorders | 328313 | 2008 | R01HD052804-01A2
Development of neural pathways in infants at risk for autism spectrum disorders (supplement) | 244282 | 2010 | 3R01HD052804-03S1

 
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