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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

ACE Center: Early detection and intervention in infants at risk for autism

Principal Investigator

Principal Investigator

Dawson, Geraldine

Description

Description

This grant provides support for an NIH Autism Center of Excellence (ACE). According to the University of Washington ACE model, early autism risk factors (genetic/familial and environmental) lead to risk processes, namely altered patterns of interaction between the child and his/her environment, which contribute to the abnormal development of neural circuitry and atypical behaviors. The goals of this project are two-fold: First, in a sample of infant siblings, the study investigates whether neurophysiological risk indices (endophenotypes) measured at 6-7 months of age will improve the ability to identify infants who will develop autism or autism-related symptoms by age 2. Second, it will assess whether it is possible to alter risk processes via early intervention with high-risk infants, thereby reducing severity of autism symptoms.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

620446

Current Award Period

Current Award Period

2007-2012

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.

Project Link

Project Link

ACE Center: Early detection and intervention in infants at risk for autism (External web link)

Institution

Institution

University of Washington

State/Country

State/Country

Washington

Project Number

Project Number

5P50HD055782-04

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

ACE Center: Early detection and intervention in infants at risk for autism | 627746 | 2009 | 5P50HD055782-03

 
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