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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Autistic traits: Life course & genetic structure

Principal Investigator

Principal Investigator

Constantino, John

Description

Description

Autism and related disorders affect 1 out of every 150 children in the US and result in profound social impairment throughout life. This study examines how autistic social impairments change over the course of childhood, how they are transmitted across generations, and which normal developmental processes they disrupt. The results of the study will aid in the search for the genes and neural abnormalities that cause autism, will enhance methods for measuring subtle but important effects of intervention, and will identify intervals in the lifespan when interventions might have their greatest impact on social development in affected children.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

547284

Current Award Period

Current Award Period

2008-2013

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2SG. Support five studies that associate specific genotypes with functional or structural phenotypes, including behavioral and medical phenotypes (e.g., nonverbal individuals with ASD and those with cognitive impairments) by 2015. IACC Recommended Budget: $22,600,000 over 5 years.

Project Link

Project Link

Autistic traits: Life course & genetic structure (External web link)

Institution

Institution

Washington University

State/Country

State/Country

Missouri

Project Number

Project Number

5R01HD042541-08

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Autistic traits: Life course & genetic structure | 573470 | 2009 | 5R01HD042541-07
Autistic traits: Life course & genetic structure | 540190 | 2008 | R01HD042541-06A1

 
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