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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

UC Davis Children's Environmental Health and Disease Prevention Research Center

Principal Investigator

Principal Investigator

Pessah, Isaac

Description

Description

Autism is a complex developmental disability which affects a person's ability to communicate and interact with others. To increase our understanding on the causes of neurodevelopmental disorders such as autism and accelerate the discovery of treatment strategies, researchers at this center study how environmental exposures to toxins interact with a person's genes and immune system to influence the risk and severity of autism. The center's research focuses on the roles of environmental factors, genes, and the immune system in a person's susceptibility to autism. Through both epidemiological and rodent models, the center's scientists are looking into how environmental triggers affect brain development. They are also examining how biological markers, such as those related to immune system dysfunction, could help clarify why some children develop these disorders. Hypotheses being tested include whether disorders such as autism are related to exposure to a wide range of environmental toxicants including methylmercury and halogenated organics (Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs). Ultimately, their aim is to improve autism diagnosis and treatment and better inform the public about managing and preventing developmental disorders such as autism. This center is co-funded by the National Institute of Environmental Health Sciences.

Funder

Funder

Environmental Protection Agency

Fiscal Year Funding

Fiscal Year Funding

756802

Current Award Period

Current Award Period

2006-2013

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SC. Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene – environment research by 2011. IACC Recommended Budget: $27,800,000 over 5 years.

Project Link

Project Link

UC Davis Children's Environmental Health and Disease Prevention Research Center (External web link)

Project Link 2

Project Link 2

UC Davis Children's Environmental Health and Disease Prevention Research Center (External web link)

Institution

Institution

University of California, Davis

State/Country

State/Country

California

Project Number

Project Number

R833292

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
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