Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Neurobiology of sociability in a mouse model system relevant to autism

Principal Investigator

Principal Investigator

Brodkin, Edward

Description

Description

Developmental variations in social behaviors and brain growth have been relatively understudied in mouse models, but such studies are needed, given the importance of developmental variations in autism. This study will use the BALB/c and C57BL/6J mouse strains to carry out developmental studies of social behaviors, including detailed analyses of social behaviors that are relevant to autism. Possible links among social behavior and brain development endophenotypes relevant to autism will also be evaluated.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

354375

Current Award Period

Current Award Period

2007-2012

Strategic Plan Question

Strategic Plan Question

Question 4: Which Treatments And Interventions Will Help?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.

Project Link

Project Link

Neurobiology of sociability in a mouse model system relevant to autism (External web link)

Institution

Institution

University of Pennsylvania

State/Country

State/Country

Pennsylvania

Project Number

Project Number

5R01MH080718-04

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Neurobiology of sociability in a mouse model system relevant to autism | 354375 | 2009 | 5R01MH080718-03
Neurobiology of sociability in a mouse model system relevant to autism | 354375 | 2008 | R01MH080718-02
Neurobiology of sociability in a mouse model system relevant to autism (supplement) | 175927 | 2009 | 3R01MH080718-03S1

 
Back to Top