Skip to content
Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Evaluating behavioral and neural effects of social skills intervention for school-age children with autism spectrum disorders

Principal Investigator

Principal Investigator

Wang, A. Ting; Soorya, Latha

Description

Description

Neuroimaging studies have found that individuals with autism spectrum disorder (ASD) show abnormally low brain activity in regions important for social processing. However, there is also evidence that activity in key brain regions can be increased significantly by providing high-functioning children with specific instructions to pay attention to important social cues, such as a speaker's facial expression or tone of voice. This suggests that interventions that use a cognitive behavioral approach to teaching social skills may be effective not only in increasing social responsiveness in terms of behavior, but also perhaps in facilitating "rewiring" that results in increased activation of normal brain circuitry. This project is testing the efficacy of a cognitive behavioral social skills intervention in a sample of high-functioning children with ASD. Participants are randomly assigned to the cognitive behavioral training or a social play control group. The investigators will use standardized assessments and functional magnetic resonance imaging (fMRI) to examine: 1) behavioral changes in social cognition and responsiveness 2) changes in the neural circuitry supporting social cognition, and 3) the relationship between changes in neural circuitry and social functioning at the behavioral level.

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2007-2010

Strategic Plan Question

Strategic Plan Question

Question 4: Which Treatments And Interventions Will Help?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 4SF. Launch five randomized controlled trials of interventions including biological signatures and other measures to predict response, and monitor quality of life and functional outcomes, in each of the following groups:
  • Five trials in infants and toddlers by 2013. IACC Recommended Budget: $30,000,000 over 5 years.
  • Three randomized controlled trials of interventions for school-aged children and/or adolescents by 2013. IACC Recommended Budget: $18,000,000 over 5 years.
  • Three trials for adults by 2014. IACC Recommended Budget: $18,000,000 over 5 years.

Project Link

Project Link

Evaluating behavioral and neural effects of social skills intervention for school-age children with autism spectrum disorders (External web link)

Institution

Institution

Mount Sinai School of Medicine

State/Country

State/Country

New York

Project Number

Project Number

2372

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Evaluating behavioral and neural effects of social skills intervention for school-age children with autism spectrum disorders | 60000 | 2009 | 2372
Evaluating behavioral and neural effects of social skills intervention for school-age children with autism spectrum disorders | 60000 | 2008 | 2372

 
Back to Top