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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Fraternal birth order effects on behavior

Principal Investigator

Principal Investigator

Breedlove, S. Marc

Description

Description

Researchers will investigate a mouse model for the effects of older brothers on behaviors that typify autistic spectrum disorder. Preliminary evidence suggests that a mammalian mother that has carried a son to term may produce antibodies that attack the nervous system of subsequent sons in utero. By learning how older brothers increase autistic-like behaviors in mice, researchers may gain insight into the development of autism and possible therapies for this disorder.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

205200

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2.2 Support at least four research projects to identify mechanisms of metabolic and/or immune system interactions with the central nervous system that may underlie the development of ASD during prenatal-postnatal life by 2010. IACC Recommended Budget: $9,800,000 over 4 years.

Project Link

Project Link

No link available.

Institution

Institution

Michigan State University

State/Country

State/Country

Michigan

Project Number

Project Number

R21MH082273-01A1

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Fraternal birth order effects on behavior | 171000 | 2009 | 5R21MH082273-02

 
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