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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

A comprehensive approach to identification of autism susceptibility genes

Principal Investigator

Principal Investigator

Geschwind, Daniel

Description

Description

The proposed study will address the possible role in autism of exposures during the peri-conceptional, gestational, perinatal, and early childhood periods, including infections, assisted reproductive technology, medications, pesticides, brominated flame retardants, and metals. It will also evaluate these environmental factors in conjunction with genes involved in xenobiotic metabolism or suggested by microarray results or by single nucleotide polymorphism (SNP) arrays. Finally, because autism manifests in heterogeneous phenotypes, researchers will examine all exposures in relation to specific subtypes of autism defined by developmental patterns such as regression versus early onset, high versus low adaptive/cognitive function, and by immunologic profiles.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

3031776

Current Award Period

Current Award Period

na

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3.4 Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene – environment research by 2011. IACC Recommended Budget: $27,800,000 over 5 years.

Project Link

Project Link

No link available.

Institution

Institution

University of California, Los Angeles

State/Country

State/Country

California

Project Number

Project Number

R01MH081754-01

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

ACE Network: A comprehensive approach to identification of autism susceptibility genes | 2823814 | 2010 | 5R01MH081754-03
ACE Network: A comprehensive approach to identification of autism susceptibility genes | 2895517 | 2009 | 5R01MH081754-02

 
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