Autism Research Database - Strategic Plan Objective Project Details | IACC

Project Element	Element Description
Project Title Project Title	Analysis of FGF17 roles and regulation in mammalian forebrain development
Principal Investigator Principal Investigator	Hoch, Renee
Description Description	The proposed studies use mouse genetics to analyze the roles and regulation of Fgf17 in the RFSC. This work will provide novel insight as to the molecular mechanisms of Fgf17 function and regulation in forebrain development. It will also lay the foundation for future collaborative projects (beyond the scope of this proposal) that will determine which roles of Fgf17 underlie the cognitive and behavioral phenotypes of Fgf17null mice. Together, these analyses will help to identify developmental processes and regulatory factors that contribute to the etiologies of autism and related psychiatric disorders.
Funder Funder	National Institutes of Health
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	$51,886
Current Award Period Current Award Period	na
Strategic Plan Question Strategic Plan Question	Question 4: Which Treatments And Interventions Will Help?
Strategic Plan Objective Strategic Plan Objective	Standardize and validate at least 20 model systems (e.g. cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012.
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	University of California, San Francisco
Institute Location Institute Location	California
Project Number Project Number	F32MH081431-01A2
Federal or Private Federal or Private	Federal
History/Related Projects History/Related Projects	Analysis of Fgf17 roles and regulation in mammalian forebrain development \| $52,154.00 \| 2010 \| 5F32MH081431-02

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