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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

ACE Center: Genetics of language & social communication: Connecting genes to brain & cognition

Principal Investigator

Principal Investigator

Geschwind, Daniel

Description

Description

This grant provides support for an NIH Autism Center of Excellence (ACE). Research from several groups suggests that studying cognitive or behavioral components of autism, or endophenotypes, may aid in identification of more homogeneous subgroups and hasten the identification of genetic loci underlying this condition. This study tests the hypothesis that speech and language related endophenotypes may underlie several of the suggestive or probable autism linkage peaks. The research uses the Autism Genetic Resource Exchange (AGRE) to identify one major and several minor linkage peaks related to speech and language delay in autistic siblings in this large autism cohort (AGRE).

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

324642

Current Award Period

Current Award Period

2007-2012

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 2SG. Support five studies that associate specific genotypes with functional or structural phenotypes, including behavioral and medical phenotypes (e.g., nonverbal individuals with ASD and those with cognitive impairments) by 2015. IACC Recommended Budget: $22,600,000 over 5 years.

Project Link

Project Link

ACE Center: Genetics of language & social communication: Connecting genes to brain & cognition (External web link)

Institution

Institution

University of California, Los Angeles

State/Country

State/Country

California

Project Number

Project Number

5P50HD055784-05

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
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