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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Developmental social neuroscience in infants at-risk for autism

Principal Investigator

Principal Investigator

McPartland, James

Description

Description

This is a mentored Research Career Development Award to support the career development of clinical investigators in patient-oriented research. This project will study the brain mechanisms involved in perceiving social information, thought to be impaired in people with autism. Brain activity and visual attention will be used to measure processing of social information in infants who are at increased risk for autism. The research will entail a longitudinal study of 60 infants at-risk for autism spectrum disorder (ASD) and 40 low-risk infants. Three experiments will be administered at 4 time points (6, 12, 18, and 24 months) to contrast social and non-social perception using static visual stimuli (mother/stranger face versus familiar/unfamiliar object), auditory stimuli (mother/stranger voice versus non-speech analogs), and dynamic audio-visual stimuli (naturalistic video clips of mother/stranger speaking versus non-biological motion and sounds). These experimental probes will map behavioral and brain specialization for social information in infancy in typical and atypical development. This research will elucidate early brain dysfunction in ASD for earlier detection and more effective intervention.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

182092

Current Award Period

Current Award Period

2010-2014

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 1LC. Identify and develop measures to assess at least three "continuous dimensions" (e.g., social reciprocity, communication disorders, and repetitive/restrictive behaviors) of ASD symptoms and severity that can be used by practitioners and/or families to assess response to intervention for people with ASD across the lifespan by 2016. IACC Recommended Budget: $18,500,000 over 5 years.

Project Link

Project Link

Developmental social neuroscience in infants at-risk for autism (External web link)

Institution

Institution

Yale University

State/Country

State/Country

Connecticut

Project Number

Project Number

5K23MH086785-02

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Developmental social neuroscience in infants at-risk for autism | 181367 | 2012 | 5K23MH086785-03

 
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