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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Using Parent Report to Identify Infants Who Are at Risk for Autism Spectrum Disorder (ASD)

Principal Investigator

Principal Investigator

Reznick, James

Description

Description

The goal of this research is to create a screening tool that will have strong sensitivity and specificity in identifying infants in their 8th through 15th month who will eventually have a diagnosis of autism spectrum disorder (ASD). This project will extend the investigators' previous work with the First Year Inventory (FYI), which is currently being used to screen infants who are 11.5 to 12.5 months old, and make it into a First Years Inventory (FYI). The FYI 3.0 incorporates recent findings regarding atypical behaviors in infants who will eventually have a diagnosis. More importantly, 9 infants who have been identified in the original cohort and screened at 12 months eventually were diagnosed with ASD, 120 developed other problems, and 569 are developing typically. These data allow for refinement of the original questions and gain better leverage on distinguishing ASD from other problems. The first aim in the present project is to obtain the normative data needed to create a developmentally sensitive risk metric. The second aim is to assess the normative cohort at 24 and 36 months to screen for symptoms of ASD and thus obtain a preliminary estimate of the FYI 3.0's sensitivity and specificity. A tool that identifies infants at risk for an eventual diagnosis of autism will facilitate research on the etiology of ASD, allow identification of children in the general population who might benefit from early intervention, support empirical tests of early interventions, and enable primary care practitioners to assess risk for ASD during routine well-baby checkups.

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

128314

Current Award Period

Current Award Period

2011-2014

Strategic Plan Question

Strategic Plan Question

Question 1: When Should I Be Concerned?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 1SB. Validate and improve the sensitivity and specificity of new or existing screening and diagnostic tools, including comparative studies of general developmental screening versus autism-specific screening tools, in both high-risk and population-based samples, including those from resource-poor international settings and those that are diverse in terms of age, socio-economic status, race, ethnicity, gender, characteristics of ASD, and general level of functioning by 2012. IACC Recommended Budget: $5,400,000 over 3 years.

Project Link

Project Link

Using Parent Report to Identify Infants Who Are at Risk for Autism Spectrum Disorder (ASD) (External web link)

Institution

Institution

University of North Carolina

State/Country

State/Country

United Kingdom

Project Number

Project Number

5946

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Using Parent Report to Identify Infants Who Are at Risk for Autism Spectrum Disorder (ASD) | 149962 | 2011 | 5946
Using Parent Report to Identify Infants Who Are at Risk for Autism Spectrum Disorder (ASD) | 137090 | 2013 | 5946
Using Parent Report to Identify Infants Who Are at Risk for Autism Spectrum Disorder (ASD) | 0 | 2014 | 5946
Using Parent Report to Identify Infants Who Are at Risk for Autism Spectrum Disorder (ASD) | 0 | 2015 | 5946

 
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