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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

ACE Center: Targeting joint engagement in infants at risk for ASD: Integrating treatment with biomarkers

Principal Investigator

Principal Investigator

Kasari, Connie

Description

Description

This grant provides support for an NIH Autism Center of Excellence (ACE). The proposed study addresses gaps in knowledge of early intervention for infants at risk of autism spectrum disorder (ASD) by testing the efficacy of an early social communication intervention (Baby JASPER), which focused on joint attention, a core deficit in young children with ASD and an important area of concern for at-risk infants. A rigorous randomized controlled treatment design will be used to compare classroom-based Baby JASPER to a hospital-based early intervention program that focuses on early motor development, cognition, adaptive and social skills (Baby Standard). Primary outcome measures will focus on social-communication and language abilities of the infants with secondary measures of parent interactions and electrophysiological measures to examine biomarkers of change with treatment as well as predictors of social communication outcomes. An effective parent-mediated intervention with a focus on core deficits may result in better language and, ultimately, improved social outcomes for at-risk infants.

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

279987

Current Award Period

Current Award Period

2012-2017

Strategic Plan Question

Strategic Plan Question

Question 4: Which Treatments And Interventions Will Help?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 4LB. Develop interventions for siblings of people with ASD with the goal of reducing risk recurrence by at least 30% by 2014. IACC Recommended Budget: $6,700,000 over 5 years.

Project Link

Project Link

ACE Center: Targeting joint engagement in infants at risk for ASD: Integrating treatment with biomarkers (External web link)

Institution

Institution

University of California, Los Angeles

State/Country

State/Country

California

Project Number

Project Number

2P50HD055784-06

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
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