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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Pediatric brain imaging

Principal Investigator

Principal Investigator

Giedd, Jay

Description

Description

It is theorized that the development of brain morphology, as opposed to snapshots in time, are more highly correlated with cognitive parameters, better predictors of clinical outcome, and more robustly distinguish groups classified by genetic variation. To capture the path of development, investigators in this study followed individuals throughout their life at two-year intervals. Investigators assessed participants through three modalities: (1) brain maging, (2) neuropsychology, and (3) genetics. Through magnetic resonance imaging (MRI), researchers compared the anatomy and physiology of brains between groups and within an individual over time. In studies of typical development, researchers performed a collection of psychological tests to assess language, executive, and social functions. Participants also provided a DNA sample for genetic testing in ongoing analyses. By combining data from these three realms researchers hope to gain insight into the dynamic interplay between brains, genes, and behavior in the developing brain. Understanding influences on trajectories of brain development may shed light on the emergence of psychopathology during childhood and adolescence and ultimately guide therapeutic interventions

Funder

Funder

National Institutes of Health

Fiscal Year Funding

Fiscal Year Funding

2419583

Current Award Period

Current Award Period

Ongoing

Strategic Plan Question

Strategic Plan Question

Question 2: How Can I Understand What Is Happening?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 2LA. Complete a large-scale, multi-disciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020. IACC Recommended Budget: $126,200,000 over 12 years.

Project Link

Project Link

Pediatric brain imaging (External web link)

Institution

Institution

National Institutes of Health

State/Country

State/Country

Maryland

Project Number

Project Number

1ZIAMH002794-11

Federal or Private?

Federal or Private?

Federal

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
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