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Question 4: Short-term Objective B
Q4.S.B : Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012.
Projects Found: 96
Total Funding: $15,303,589
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Simons Foundation A zebrafish model to identify epigenetic mechanisms relevant to autism $0
$0 King's College London
Simons Foundation A mouse model of top-down interactions $0
$0 ROCKEFELLER UNIVERSITY
Simons Foundation Understanding copy number variants associated with autism $125,000
$125,000 Duke University
Simons Foundation Behavioral evaluation of a novel autism mouse model $0
$0 Shriners Hospitals for Children - Northern California
Simons Foundation 16p11.2 deletion mice: autism-relevant phenotypes and treatment discovery $0
$0 University of California, Davis
Autism Speaks Novel approaches to enhance social cognition by stimulating central oxytocin release $0
$0 Emory University
Simons Foundation Functional connectivity in monogenic mouse models of autism $0
$0 Fondazione Istituto Italiano di Tecnologia
Simons Foundation Analysis of oxytocin function in brain circuits processing social cues $125,000
$125,000 Harvard University
Simons Foundation The Role of Cation/Proton Exchanger NHE9 in Autism $125,000
$125,000 University of California, San Francisco
Simons Foundation How do autism-related mutations affect basal ganglia function? $125,000
$125,000 University of California, Berkeley
Interagency Autism Coordinating Committee (IACC)
Autism Research Database (AFD)
Q4.S.B: Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. 
