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Question 4: Short-term Objective B
Q4.S.B : Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012.
Projects Found: 96
Total Funding: $15,303,589
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National Institutes of Health Mechanisms of circuit failure and treatments in patient-derived neurons in autism $406,250
$406,250 BROWN UNIVERSITY
National Institutes of Health THE GENETIC AND NEUROANATOMICAL ORIGIN OF SOCIAL BEHAVIOR $391,250
$391,250 Baylor College of Medicine
Simons Foundation In Vivo Functional Analysis of Autism Candidate Genes $123,750
$123,750 Baylor College of Medicine
Autism Speaks Preclinical Autism Consortium for Therapeutics (PACT)- Boston Children's Hospital $0
$0 Boston Children's Hospital
Brain & Behavior Research Foundation Rebuilding Inhibition in the Autistic Brain $24,840
$24,840 Brandeis University
Simons Foundation Cellular models for autism de novo mutations using human stem cells $125,000
$125,000 Broad Institute, Inc.
National Institutes of Health Preclinical evaluation of NMDA receptor antagonists for treating Rett Syndrome $396,250
$396,250 CASE WESTERN RESERVE UNIVERSITY
Simons Foundation Analysis of autism-associated alleles in C. elegans $108,061
$108,061 California Institute of Technology
Brain & Behavior Research Foundation Pinpointing Genes Underlying Autism in Chromosomal Region 16p11.2 $1,250
$1,250 Cold Spring Harbor Laboratory
Simons Foundation 16p11.2: Defining the gene(s) responsible (grant 1) $212,100
$212,100 Cold Spring Harbor Laboratory
Interagency Autism Coordinating Committee (IACC)
Autism Research Database (AFD)
Q4.S.B: Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. 
