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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 

Question 2: Short-term Objective D

green dot 2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Projects Found: 57
Total Funding: 13162905
Records
Project Title Funding Funding Institution

Project Title

Investigation of postnatal drug intervention's potential in rescuing the symptoms of fragile X syndrome in adult mice
$0

Funding

0

Institution

Massachusetts Institute of Technology

Project Title

In-vivo imaging of neuronal structure and function in a reversible mouse model for autism.
$28,000

Funding

28000

Institution

Baylor College of Medicine

Project Title

Molecular basis of autism associated with human adenylosuccinate lyase gene defects
$0

Funding

0

Institution

University of Delaware

Project Title

Elucidation and rescue of amygdala abnormalities in the Fmr1 mutant mouse model of fragile X syndrome
$150,000

Funding

150000

Institution

George Washington University

Project Title

Developmental versus acute mechanisms mediating altered excitatory synaptic function in the fragile X syndrome mouse model
$127,500

Funding

127500

Institution

University of Texas Southwestern Medical Center

Project Title

Visual system connectivity in a high-risk model of autism
$0

Funding

0

Institution

Children's Hospital Boston

Project Title

The role of the autism-associated gene tuberous sclerosis complex 2 (TSC2) in presynaptic development
$56,000

Funding

56000

Institution

University of California, San Diego

Project Title

Neural circuit deficits in animal models of Rett syndrome
$44,000

Funding

44000

Institution

Cold Spring Harbor Laboratory

Project Title

The functional link between DISC1 and neuroligins: Two genetic factors in the etiology of autism
$0

Funding

0

Institution

Children's Memorial Hospital, Chicago

Project Title

Modulation of fxr1 splicing as a treatment strategy for autism in fragile X syndrome
$158,649

Funding

158649

Institution

Stanford University

 
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