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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 

Question 2: Short-term Objective D

green dot 2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Projects Found: 83
Total Funding: 18452242
Records
Project Title Funding Funding Institution

Project Title

The microRNA pathway in translational regulation of neuronal development
$352,647

Funding

352647

Institution

University of Massachusetts Medical School

Project Title

Neural mechanisms underlying autism behaviors in SCN1A mutant mice
$94,903

Funding

94903

Institution

University of Washington

Project Title

Dysregulation of mTOR signaling in fragile X syndrome
$415,000

Funding

415000

Institution

Albert Einstein College of Medicine of Yeshiva University

Project Title

Mouse models of human autism spectrum disorders: Gene targeting in specific brain regions
$400,000

Funding

400000

Institution

University of Texas Southwestern Medical Center

Project Title

Mechanisms of synapse elimination by autism-linked genes
$434,883

Funding

434883

Institution

University of Texas Southwestern Medical Center

Project Title

Elucidation and rescue of amygdala abnormalities in the Fmr1 mutant mouse model of fragile X syndrome
$150,000

Funding

150000

Institution

George Washington University

Project Title

Emergence and stability of autism in fragile X syndrome
$358,000

Funding

358000

Institution

University of South Carolina

Project Title

Mechanisms of mGluR5 function and dysfunction in mouse autism models
$406,760

Funding

406760

Institution

University of Texas Southwestern Medical Center

Project Title

BDNF and the restoration of synaptic plasticity in fragile X and autism
$470,063

Funding

470063

Institution

University of California, Irvine

Project Title

Study of fragile X mental retardation protein in synaptic function and plasticity
$317,077

Funding

317077

Institution

University of Texas Southwestern Medical Center

 
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