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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 

Question 2: Short-term Objective D

yellow dot 2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Projects Found: 48
Total Funding: 9171542
Records
Project Title Funding Funding Institution

Project Title

Investigation of postnatal drug intervention's potential in rescuing the symptoms of fragile X syndrome in adult mice
$30,000

Funding

30000

Institution

Massachusetts Institute of Technology

Project Title

Neural circuit deficits in animal models of Rett syndrome
$0

Funding

0

Institution

Cold Spring Harbor Laboratory

Project Title

The role of the autism-associated gene tuberous sclerosis complex 2 (TSC2) in presynaptic development
$54,000

Funding

54000

Institution

University of California, San Diego

Project Title

Molecular basis of autism associated with human adenylosuccinate lyase gene defects
$30,000

Funding

30000

Institution

University of Delaware

Project Title

Identification of UBE3A substrates using proteomic profiling in Drosophila
$0

Funding

0

Institution

University of Tennessee Health Science Center

Project Title

An adult brain-specific mouse model of neuronal TSC inactivation
$60,000

Funding

60000

Institution

Massachusetts General Hospital

Project Title

Visual system connectivity in a high-risk model of autism
$41,000

Funding

41000

Institution

Children's Hospital Boston

Project Title

Developmental versus acute mechanisms mediating altered excitatory synaptic function in the fragile X syndrome mouse model
$0

Funding

0

Institution

University of Texas Southwestern Medical Center

Project Title

The functional link between DISC1 and neuroligins: Two genetic factors in the etiology of autism
$110,250

Funding

110250

Institution

Children's Memorial Hospital, Chicago

Project Title

The microRNA pathway in translational regulation of neuronal development
$417,813

Funding

417813

Institution

J. David Gladstone Institutes

 
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