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Question 3: Short-term Objective A
Q3.S.A : Coordinate and implement the inclusion of approximately 20,000 subjects for genome-wide association studies, as well as a sample of 1,200 for sequencing studies to examine more than 50 candidate genes by 2011. Studies should investigate factors contributing to phenotypic variation across individuals that share an identified genetic variant and stratify subjects according to behavioral, cognitive, and clinical features. IACC Recommended Budget: $43,700,000 over 4 years.
Projects Found: 18
Total Funding: $5,015,006
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Autism Science Foundation Uncovering the Spectrum of De Novo Mutation in Autism through Whole Genome Sequencing $35,000
$35,000 University of California, San Diego
Autism Speaks Advanced Autism Genetics: Biological Subgroups, Diagnostic Classification, and Resilience. $30,000
$30,000 State University of New York, Upstate Medical University
Autism Speaks Genomic influences on developmental course and outcome in Infants at risk of ASD: A Baby Siblings Research Consortium (BSRC) Study $0
$0 University of Alberta
Autism Speaks Genomic influences on development and outcomes in Infants at risk of ASD $0
$0 University of Alberta
Center for Autism and Related Disorders An exploration of genetic and behavioral variables in Autism Spectrum Disorder $18,200
$18,200 Center for Autism and Related Disorders (CARD)
National Institutes of Health 4/4 The Autism Sequencing Consortium: Autism gene discovery in the >20,000 exomes (supplement) $919,964
$919,964 UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
National Institutes of Health 4/4 The Autism Sequencing Consortium: Autism gene discovery in >20,000 exomes $676,656
$676,656 UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
National Institutes of Health Rapid Phenotyping for Rare Variant Discovery in Autism $453,878
$453,878 University of California, Los Angeles
National Institutes of Health 2/4-The Autism Sequencing Consortium: Autism gene discovery in >20,000 exomes $415,893
$415,893 BROAD INSTITUTE, INC.
National Institutes of Health 2/4-The Autism Sequencing Consortium: Autism gene discovery in >20,000 exomes $157,618
$157,618 BROAD INSTITUTE, INC.
Interagency Autism Coordinating Committee (IACC)
Autism Research Database (AFD)
Q3.S.A: Coordinate and implement the inclusion of approximately 20,000 subjects for genome-wide association studies, as well as a sample of 1,200 for sequencing studies to examine more than 50 candidate genes by 2011. Studies should investigate factors contributing to phenotypic variation across individuals that share an identified genetic variant and stratify subjects according to behavioral, cognitive, and clinical features. IACC Recommended Budget: $43,700,000 over 4 years.
