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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 

Question 3: Short-term Objective J

green dot 3SJ. Support at least three studies that focus on the role of epigenetics in the etiology of ASD, including studies that include assays to measure DNA methylations and histone modifications and those exploring how exposures may act on maternal or paternal genomes via epigenetic mechanisms to alter gene expression, by 2012. IACC Recommended Budget: $20,000,000 over 5 years.

Projects Found: 19
Total Funding: 5341237
Records
Project Title Funding Funding Institution

Project Title

Studies of postmortem brain searching for epigenetic defects causing autism
$200,000

Funding

200000

Institution

Baylor College of Medicine

Project Title

Human neurobehavioral phenotypes associates with the extended PWS/AS domain
$628,392

Funding

628392

Institution

Baylor College of Medicine

Project Title

The role of the Rett gene, chromosome 15q11-q13, other genes, and epigenetics
$1,187

Funding

1187

Institution

Baylor College of Medicine

Project Title

Genome-wide analyses of DNA methylation in autism
$200,000

Funding

200000

Institution

Massachusetts General Hospital

Project Title

In vivo function of neuronal activity-induced MeCP2 phosphorylation
$292,721

Funding

292721

Institution

University of Wisconsin - Madison

Project Title

Discordant monozygotic twins as a model for genetic-environmental interaction in autism
$0

Funding

0

Institution

Johns Hopkins University

Project Title

Epigenetic and transcriptional dysregulation in autism spectrum disorder
$764,608

Funding

764608

Institution

University of California, Los Angeles

Project Title

Identification of aberrantly methylated genes in autism: The role of advanced paternal age
$0

Funding

0

Institution

Research Foundation for Mental Hygiene, Inc.

Project Title

Maternal supplementation of folic acid and function of autism gene synaptic protein Shank3 in animal model
$87,793

Funding

87793

Institution

Baylor College of Medicine

Project Title

Discordant monozygotic twins as a model for genetic-environmental interaction in autism
$0

Funding

0

Institution

Kennedy Krieger Institute

 
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